On the article " Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window"
- PMID: 29611552
- PMCID: PMC5879527
- DOI: 10.21037/atm.2017.11.31
On the article " Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window"
Conflict of interest statement
Conflicts of Interest: PC Wong and J Yang are employees of Bristol-Myers Squibb.
Comment on
-
Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window.Ann Transl Med. 2017 Dec;5(23):464. doi: 10.21037/atm.2017.09.10. Ann Transl Med. 2017. PMID: 29285497 Free PMC article. No abstract available.
References
-
- Callejo MF, Colin J, Desmeules S, et al. Mutagenesis Studies Reveal Minimal Impact of the Human A120T Variant of Protease-activated Receptor 4 on Receptor Function or Pharmacological Response to Potent and Selective Antagonists. Stroke 2016;47:AWP263.
-
- Ismat FA, Ma X, Wang Z, et al. Phase I Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Oral Protease-activated Receptor-4 Antagonist BMS-986120. Stroke 2016;47:ATMP91.
-
- Wilson SJ, Ismat FA, Narayan H, et al. Protease-Activated Receptor Type 4 (PAR-4) Antagonism With BMS-986120 Selectively Inhibits Human Thrombus Formation Under Conditions of High Shear Stress. Circulation 2016;134:A18771.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources