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Comment
. 2018 Apr 3;27(4):703-705.
doi: 10.1016/j.cmet.2018.03.006.

Eating the Beast: Dietary Protein and Anticancer Immunity

Douglas R Green  1
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Eating the Beast: Dietary Protein and Anticancer Immunity

Douglas R Green. Cell Metab. .
Free article

Abstract

Studies on the impact of diet on cancer progression have predominantly focused on the metabolic demands of the tumor. In this issue of Cell Metabolism, Rubio-Patiño et al. (2018) examine how a small reduction in dietary protein effectively commandeers the adaptive immune response to attack the tumor, highlighting a role for endoplasmic reticulum stress.

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  • Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.
    Rubio-Patiño C, Bossowski JP, De Donatis GM, Mondragón L, Villa E, Aira LE, Chiche J, Mhaidly R, Lebeaupin C, Marchetti S, Voutetakis K, Chatziioannou A, Castelli FA, Lamourette P, Chu-Van E, Fenaille F, Avril T, Passeron T, Patterson JB, Verhoeyen E, Bailly-Maitre B, Chevet E, Ricci JE. Rubio-Patiño C, et al. Cell Metab. 2018 Apr 3;27(4):828-842.e7. doi: 10.1016/j.cmet.2018.02.009. Cell Metab. 2018. PMID: 29551590

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