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Comment
. 2018 Apr 3;26(4):527-528.
doi: 10.1016/j.str.2018.03.008.

A Pseudo-Kinase Double Act

Franziska Preuß  1 , Sebastian Mathea  2 , Stefan Knapp  3
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A Pseudo-Kinase Double Act

Franziska Preuß et al. Structure. .
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  • A Pseudo-Kinase Double Act.
    Preuß F, Mathea S, Knapp S. Preuß F, et al. Structure. 2018 Nov 6;26(11):1564. doi: 10.1016/j.str.2018.10.019. Structure. 2018. PMID: 30403994 No abstract available.

Abstract

Pragmin is a catalytically inactive pseudo-kinase that is important in regulating cellular growth and adhesion. In this issue of Structure, Lecointre et al. (2018) present the structure of Pragmin, illustrating a dimerization domain flanking its pseudo-kinase domain that is important for Pragmin-mediated activation of the non-receptor tyrosine kinase CSK.

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