Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May;49(5):1286-1289.
doi: 10.1161/STROKEAHA.117.018987. Epub 2018 Apr 4.

Thrombectomy for M1-Middle Cerebral Artery Occlusion: Angiographic Aspect of the Arterial Occlusion and Recanalization: A Preliminary Observation

Arturo Consoli  1   2 , Andrea Rosi  2 , Oguzhan Coskun  3 , Sergio Nappini  2 , Federico Di Maria  3 , Leonardo Renieri  2 , Nicola Limbucci  2 , Georges Rodesch  3 , Salvatore Mangiafico  2 , Jean-Pierre Decroix  3 , Maeva Kyheng  4 , Julien Labreuche  4 , Bertrand Lapergue  3
Affiliations

Thrombectomy for M1-Middle Cerebral Artery Occlusion: Angiographic Aspect of the Arterial Occlusion and Recanalization: A Preliminary Observation

Arturo Consoli et al. Stroke. 2018 May.

Abstract

Background and purpose: Despite the recent technical evolution of the endovascular treatment of acute ischemic stroke, late and incomplete recanalization can be achieved after several maneuvers but with a potentially higher risk of futile reperfusion and complications, such as clot fragmentation. The aim of this article is to investigate the impact of the angiographic phenotype of M1-middle cerebral artery occlusions, classified as regular and irregular in aspect, on the results of treatment by stent retrievers (SRs) or contact aspiration (CA).

Methods: From January to April 2016, 84 consecutive patients, admitted for acute ischemic stroke with a middle cerebral artery occlusion, were treated by endovascular therapy. Among them, 60 patients (26M, 34F, median age, 70.5; interquartile range, 58.5-80.0) were treated by SR (25/60, 41.7%) or CA (35/60, 58.3%) as a first-line approach in 2 experienced centers. Patients' characteristics, timing, and procedural data were prospectively recorded and compared between the 2 study subgroups (regular and irregular phenotype).

Results: A regular phenotype at the occlusion site was observed in 24 patients (40%). Among these, successful recanalization after the first-line strategy (Thrombolysis in Cerebral Infarction 2b-3) was achieved in 100% of patients treated by CA and in only 33.3% of patients treated by SR (P=0.001). For irregular phenotypes, SR achieved Thrombolysis in Cerebral Infarction 2b-3 in 73.9% and CA, in 38.5% (P=0.036) of cases. Among regular phenotype patients, the average number of maneuvers was 1.3 (median, 1; range 1-3) with first-line CA and 2.7 (median, 3; range 1-5) with first-line SR (P=0.008).

Conclusions: The angiographic phenotype of the occlusion site may be associated with a different response to SR and CA in this preliminary experience.

Keywords: angiography; middle cerebral artery; phenotype; reperfusion; thrombectomy.

PubMed Disclaimer