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Review
. 2018 Aug;18(4):271-277.
doi: 10.1136/practneurol-2017-001789. Epub 2018 Apr 4.

Zika virus infection in the returning traveller: what every neurologist should know

Sonja Emily Leonhard #  1 , Suzannah Lant #  2 , Bart C Jacobs  3 , Annelies Wilder-Smith  4 , Maria Lucia Brito Ferreira  5 , Tom Solomon  2   6   7 , Hugh John Willison  8
Affiliations
Review

Zika virus infection in the returning traveller: what every neurologist should know

Sonja Emily Leonhard et al. Pract Neurol. 2018 Aug.

Abstract

Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers with Zika virus infection have been reported and the virus continues to spread to previously unaffected regions. This review provides an overview of Zika virus-associated neurological disease and aims to support neurologists who may encounter patients returning from endemic areas.

Keywords: Guillain-Barré syndrome; clinical neurology; neuroimmunology; neurovirology; zika virus.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Aedes mosquito.
Figure 2
Figure 2
Map of high- and low-risk areas for infection.
Figure 3
Figure 3
MR scan of brain fluid-attenuated inversion recovery (FLAIR) (A) and short tau inversion recovery (STIR) (B, C) showing asymmetrical hyperintensities affecting the left nucleocapsular region, thalamus and insula (A), and hyperintense longitudinally extensive lesions in the spinal cord. (Copyright © S Karger AG, Basel; Niemeyer et al36).
Figure 4
Figure 4
Algorithm for laboratory investigation of suspected Zika virus infection. CHIKV, chikungunya virus; CSF, cerebrospinal fluid; DENV, dengue virus.
See this image and copyright information in PMC

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