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Review
. 2019 Nov 28;37(50):7437-7442.
doi: 10.1016/j.vaccine.2018.02.089. Epub 2018 Apr 3.

Vaccination against the human cytomegalovirus

Stanley A Plotkin  1 , Suresh B Boppana  2
Affiliations
Review

Vaccination against the human cytomegalovirus

Stanley A Plotkin et al. Vaccine. .

Abstract

The human cytomegalovirus (HCMV) is the most important infectious cause of congenital abnormalities and also of infectious complications of transplantation. The biology of the infection is complex and acquired immunity does not always prevent reinfection. Nevertheless, vaccine development is far advanced, with numerous candidate vaccines being tested, both live and inactivated. This article summarizes the status of the candidate vaccines.

Keywords: CMV; Congenital infection; Deafness; Pentamer; Reinfection.

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References

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