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Review
. 2018 Mar 20:7:339.
doi: 10.12688/f1000research.13380.1. eCollection 2018.

Cluster headache: new targets and options for treatment

Patty Doesborg  1 , Joost Haan  1   2
Affiliations
Review

Cluster headache: new targets and options for treatment

Patty Doesborg et al. F1000Res. .

Abstract

Cluster headache is a severe headache disorder with considerable impact on quality of life. The pathophysiology of the disease remains poorly understood. With few specific targets for treatment, current guidelines mainly include off-label treatment with medication. However, new targets for possible treatment options are emerging. Calcitonin gene-related peptide (CGRP)-targeted medication could become the first (cluster) headache-specific treatment option. Other exciting new treatment options include invasive and non-invasive neuromodulation techniques. Here, we provide a short overview of new targets and treatment options that are being investigated for cluster headache.

Keywords: Calcitonin gene-related peptide targeted therapies; Cluster headache; treatment targets.

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Conflict of interest statement

No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

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