Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Apr;78(6):693-697.
doi: 10.1007/s40265-018-0899-1.

Baloxavir: First Global Approval

Young-A Heo  1
Affiliations
Review

Baloxavir: First Global Approval

Young-A Heo. Drugs. 2018 Apr.

Abstract

Baloxavir marboxil (Xofluza™; baloxavir) is an oral cap-dependent endonuclease inhibitor that has been developed by Roche and Shionogi. The drug blocks influenza virus proliferation by inhibiting the initiation of mRNA synthesis. In February 2018, baloxavir received its first global approval in Japan for the treatment of influenza A or B virus infections. Phase III development is underway in the USA, EU and other countries for this indication. This article summarized the milestones in the development of baloxavir leading to this first global approval for influenza A or B virus infections.

PubMed Disclaimer

References

    1. Nature. 2006 Jul 27;442(7101):448-52 - PubMed
    1. Influenza Other Respir Viruses. 2017 May;11(3):240-246 - PubMed

MeSH terms

LinkOut - more resources