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Review
. 2018 Aug 15;198(4):440-446.
doi: 10.1164/rccm.201801-0120PP.

Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine

Affiliations
Review

Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine

Paul A Reyfman et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
A conceptual depiction of respiratory health trajectories over the lifespan (adapted from the seminal work of Fletcher and Peto [33] and updated to incorporate work of Kalhan and colleagues [13] and Lange and colleagues [12]). We believe efforts toward developing a comprehensive definition of respiratory health will be aided by conceptualizing the major contributors to the development of impaired respiratory health as influencing either peak lung function in young adulthood (pulmonary “reserve”) or the rate of decline in lung function (pulmonary “susceptibility”). Multiple risk factors are associated with an individual’s reserve and susceptibility, which may ultimately contribute to the development of chronic respiratory disease (Table 1).

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