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Comment

. 2018 Apr 6;3(22):eaat6418.

doi: 10.1126/sciimmunol.aat6418.

The right angle on IL-2 therapy

Ira Surolia¹, Shiv Pillai¹

Affiliations

Affiliation

¹ Division of Hematology-Oncology, Columbia University Medical Center, New York, NY 10032, USA. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA 02139, USA. Email: pillai@helix.mgh.harvard.edu.

PMID: 29626173
DOI: 10.1126/sciimmunol.aat6418

Comment

The right angle on IL-2 therapy

Ira Surolia et al. Sci Immunol. 2018.

. 2018 Apr 6;3(22):eaat6418.

doi: 10.1126/sciimmunol.aat6418.

Authors

Ira Surolia¹, Shiv Pillai¹

Affiliation

¹ Division of Hematology-Oncology, Columbia University Medical Center, New York, NY 10032, USA. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA 02139, USA. Email: pillai@helix.mgh.harvard.edu.

PMID: 29626173
DOI: 10.1126/sciimmunol.aat6418

Abstract

Engineered cytokines are able to improve immunotherapy in mouse tumor models.

Copyright © 2018, American Association for the Advancement of Science.

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Comment on

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.
Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Sockolosky JT, et al. Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246. Science. 2018. PMID: 29496879 Free PMC article.

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