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. 2018 May;18(5):289-290.
doi: 10.1038/nri.2018.26. Epub 2018 Apr 9.

Discovering transcriptional signatures of disease for diagnosis versus mechanism

Julie G Burel  1 , Bjoern Peters  1
Affiliations

Discovering transcriptional signatures of disease for diagnosis versus mechanism

Julie G Burel et al. Nat Rev Immunol. 2018 May.

Abstract

Transcriptional signatures of disease can be used for diagnosis or to gain insight into disease mechanisms. This Comment article discusses the different sets of criteria that should be considered for the optimal design of investigations addressing these two purposes, using examples from the study of tuberculosis.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

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