Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May 1;178(5):657-664.
doi: 10.1001/jamainternmed.2018.0411.

Dialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs

Manjula Kurella Tamura  1   2 , I-Chun Thomas  1   2 , Maria E Montez-Rath  2 , Kristopher Kapphahn  3 , Manisha Desai  3 , Randall C Gale  4   5 , Steven M Asch  4   5
Affiliations

Dialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs

Manjula Kurella Tamura et al. JAMA Intern Med. .

Erratum in

  • Numeric Errors in Table 1.
    [No authors listed] [No authors listed] JAMA Intern Med. 2018 Nov 1;178(11):1568. doi: 10.1001/jamainternmed.2018.6396. JAMA Intern Med. 2018. PMID: 31381668 Free PMC article. No abstract available.

Abstract

Importance: The benefits of maintenance dialysis for older adults with end-stage renal disease (ESRD) are uncertain. Whether the setting of pre-ESRD nephrology care influences initiation of dialysis and mortality is not known.

Objective: To compare initiation of dialysis and mortality among older veterans with incident kidney failure who received pre-ESRD nephrology care in fee-for-service Medicare vs the Department of Veterans Affairs (VA).

Design, setting, and participants: Retrospective cohort study of patients from the US Medicare and VA health care systems evaluated 11 215 veterans aged 67 years or older with incident kidney failure between January 1, 2008, and December 31, 2011. Data analysis was performed March 15, 2016, through September 20, 2017.

Exposures: Pre-ESRD nephrology care in Medicare vs VA health care systems.

Main outcome and measures: Dialysis treatment and death within 2 years.

Results: Of the 11 215 patients included in the study, 11 085 (98.8%) were men; mean (SD) age was 79.1 (6.9) years. Within 2 years of incident kidney failure, 7071 (63.0%) of the patients started dialysis and 5280 (47.1%) died. Patients who received pre-ESRD nephrology care in Medicare were more likely to undergo dialysis compared with patients who received pre-ESRD nephrology care in VA (82% vs 53%; adjusted risk difference, 28 percentage points; 95% CI, 26-30 percentage points). Differences in dialysis initiation between Medicare and VA were more pronounced among patients aged 80 years or older and patients with dementia or metastatic cancer, and less pronounced among patients with paralysis (P < .05 for interaction). Two-year mortality was higher for patients who received pre-ESRD care in Medicare compared with VA (53% vs 44%; adjusted risk difference, 5 percentage points; 95% CI, 3-7 percentage points). The findings were similar in a propensity-matched analysis.

Conclusions and relevance: Veterans who receive pre-ESRD nephrology care in Medicare receive dialysis more often yet are also more likely to die within 2 years compared with those in VA. The VA's integrated health care system and financing appear to favor lower-intensity treatment for kidney failure in older patients without a concomitant increase in mortality.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure 1.
Figure 1.. Cohort Flowchart
Derivation of analytic cohort of veterans with incident kidney failure. eGFR indicates estimated glomerular filtration rate; ESRD, end-stage renal disease; and VA, Veterans Affairs.
Figure 2.
Figure 2.. Relative Risk of Dialysis Treatment Within 2 Years of Incident Kidney Failure Among Patients Receiving Pre–End Stage Renal Disease Nephrology Care Through Medicare vs Veterans Affairs
Measured in main analytic cohort (N = 11 215) of patients receiving care through Veterans Affairs vs Medicare. The dotted line indicates overall effect of higher dialysis use in Medicare. RR indicates relative risk.
Figure 3.
Figure 3.. Frequency of Death Within 2 Years of Incident Kidney Failure Among Patients Receiving Pre–End Stage Renal Disease Nephrology Care Through Medicare vs Veterans Affairs
Measured in main analytic cohort (N = 11 215) of patients receiving care through Veterans Affairs vs Medicare.
See this image and copyright information in PMC

Comment in

References

    1. Williams AW, Dwyer AC, Eddy AA, et al. ; American Society of Nephrology Quality, and Patient Safety Task Force . Critical and honest conversations: the evidence behind the “Choosing Wisely” campaign recommendations by the American Society of Nephrology. Clin J Am Soc Nephrol. 2012;7(10):1664-1672. - PubMed
    1. Kurella Tamura M, Covinsky KE, Chertow GM, Yaffe K, Landefeld CS, McCulloch CE. Functional status of elderly adults before and after initiation of dialysis. N Engl J Med. 2009;361(16):1539-1547. - PMC - PubMed
    1. Carson RC, Juszczak M, Davenport A, Burns A. Is maximum conservative management an equivalent treatment option to dialysis for elderly patients with significant comorbid disease? Clin J Am Soc Nephrol. 2009;4(10):1611-1619. - PMC - PubMed
    1. Moss AH. Revised dialysis clinical practice guideline promotes more informed decision-making. Clin J Am Soc Nephrol. 2010;5(12):2380-2383. - PubMed
    1. O’Hare AM, Rodriguez RA, Hailpern SM, Larson EB, Kurella Tamura M. Regional variation in health care intensity and treatment practices for end-stage renal disease in older adults. JAMA. 2010;304(2):180-186. - PMC - PubMed

Publication types