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Case Reports
. 2018 Apr 10;18(1):20.
doi: 10.1186/s12893-018-0351-1.

Successful pulmonary arterial embolization followed by curative surgery for a lepidic predominant lung adenocarcinoma with severe hypoxemia

Louise Sebane  1 , Mostafa El-Hajjam  2 , Philippe Puyo  3 , Elisabeth Longchampt  4 , Etienne Giroux Leprieur  5   6
Affiliations
Case Reports

Successful pulmonary arterial embolization followed by curative surgery for a lepidic predominant lung adenocarcinoma with severe hypoxemia

Louise Sebane et al. BMC Surg. .

Abstract

Background: Lepidic predominant adenocarcinoma is characterized by frequent refractory hypoxemia due to intrapulmonary shunting. Severe hypoxemia can induce perioperative complications in case of thoracic surgery.

Case presentation: We report a case of a 67 year-old woman with localized lepidic adenocarcinoma in the right lower lobe with severe hypoxemia. A selective arterial lung embolization allowed an instantaneous correction of the hypoxemia, and a curative lobectomy was safely performed 1 week after without any complication. The staging was pT3N0M0, and the patient received adjuvant chemotherapy.

Conclusions: This is the first case-report of successful endovascular embolization before curative surgery for a lepidic predominant lung adenocarcinoma.

Keywords: Arterial embolization; Hypoxemia; Lepidic adenocarcinoma; Non-small cell lung cancer; Thoracic surgery.

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Conflict of interest statement

Authors’ information

Not applicable.

Ethics approval and consent to participate

Written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent is available for review.

This case report study was carried out respecting the Declaration of Helsinki in its current version. Ethical approval: not applicable.

Consent for publication

Written informed consent was obtained from the patient for publication of this Case report and any accompanying images.

Competing interests

The authors declare that they have no competing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
CT-scan showing ground-glass opacities and alveolar consolidation in the right lower lobe
Fig. 2
Fig. 2
Successful intravascular occlusion of the right lower lung artery by coils and plugs
See this image and copyright information in PMC

References

    1. Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol. 2011;6:244–285. doi: 10.1097/JTO.0b013e318206a221. - DOI - PMC - PubMed
    1. Wolinsky H, Lin A, Williams MH., Jr Lung perfusion in bronchiolo-alveolar carcinoma. A case report. Am Rev Respir Dis. 1969;99:585–589. - PubMed
    1. Barlesi F, Doddoli C, Thomas P, Kleisbauer JP, Giudicelli R, Fuentes P. Bilateral bronchioloalveolar lung carcinoma: is there a place for palliative pneumonectomy? Eur J Cardiothorac Surg. 2001;20(6):1113–1116. doi: 10.1016/S1010-7940(01)00977-0. - DOI - PubMed
    1. Chetty KG, Dick C, McGovern J, Conroy RM, Mahutte CK. Refractory hypoxemia due to intrapulmonary shunting associated with bronchioloalveolar carcinoma. Chest. 1997;111(4):1120–1121. doi: 10.1378/chest.111.4.1120. - DOI - PubMed
    1. Falcoz PE, Hoan NT, Le Pimpec-Barthes F, Riquet M. Severe hypoxemia due to intrapulmonary shunting requiring surgery for bronchioloalveolar carcinoma. Ann Thorac Surg. 2009;88(1):287–288. doi: 10.1016/j.athoracsur.2008.12.031. - DOI - PubMed

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