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Comment
. 2018 Apr 24;115(17):4317-4319.
doi: 10.1073/pnas.1804084115. Epub 2018 Apr 9.

New insight into the early stages of biofilm formation

Catherine R Armbruster  1 , Matthew R Parsek  2
Affiliations
Comment

New insight into the early stages of biofilm formation

Catherine R Armbruster et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
A diagram depicting early events in biofilm formation. Planktonic cells that have not previously encountered cells and are exhibiting low cAMP levels are called surface naive. These cells initially exhibit very brief, transient interactions with a surface called reversible attachment. After each successive attachment/detachment event, the levels of cAMP gradually build due to the activity of the Pil-Chp surface-sensing system. Planktonic cells that have recently associated with surfaces and exhibit high cAMP levels are called surface sentient. These increases in cAMP eventually result in bacteria remaining associated with the surface for longer periods of time and ultimately contribute to progression to the irreversible attachment stage, where cells remain surface adhered and ultimately develop into biofilms.
See this image and copyright information in PMC

Comment on

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