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Comment
. 2018 Apr 10;24(4):388-390.
doi: 10.1038/nm.4531.

Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys

Steven A Goldman  1
Affiliations
Comment

Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys

Steven A Goldman. Nat Med. .
No abstract available

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Figures

Figure
Figure
Rosenzweig et al., transplant human neural progenitor cells (NPCs) labeled with GFP into the hemisected monkey spinal cord, a model that mimics severe human SCI. They find that after 20 weeks, donor neurons extend fibers into the host spinal cord, while receiving inputs from the host as well, so that the graft can serve as a functional bridge across the injury site, resulting in partial restoration of motor function.
See this image and copyright information in PMC

Comment on

  • Restorative effects of human neural stem cell grafts on the primate spinal cord.
    Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH. Rosenzweig ES, et al. Nat Med. 2018 May;24(4):484-490. doi: 10.1038/nm.4502. Epub 2018 Feb 26. Nat Med. 2018. PMID: 29480894 Free PMC article.

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