Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing Cells
- PMID: 29634936
- DOI: 10.1016/j.devcel.2018.03.015
Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing Cells
Abstract
During mitosis, animal cells disassemble focal adhesions and round up while remaining attached to the substrata via actin cables and unknown adhesive structures. In this issue of Developmental Cell, Dix et al. (2018) describe integrin-positive adhesions, devoid of classical focal adhesion components, that persist throughout mitosis to contribute to re-spreading.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division.Dev Cell. 2018 Apr 9;45(1):132-145.e3. doi: 10.1016/j.devcel.2018.03.009. Dev Cell. 2018. PMID: 29634933
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