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. 2018 May;146(7):920-930.
doi: 10.1017/S0950268818000766. Epub 2018 Apr 11.

HIV and viral hepatitis coinfection analysis using surveillance data from 15 US states and two cities

K A Bosh  1 , J R Coyle  2 , V Hansen  3 , E M Kim  3 , S Speers  4 , M Comer  5 , L M Maddox  5 , S Khuwaja  6 , W Zhou  6 , A Jatta  7 , R Mayer  7 , A D Brantley  8 , N W Muriithi  8 , R Bhattacharjee  9 , C Flynn  9 , L Bouton  10 , B John  10 , J Keusch  2 , C A Barber  11 , K Sweet  11 , C Ramaswamy  12 , E F Westheimer  12 , L VanderBusch  13 , A Nishimura  14 , A Vu  14 , L Hoffman-Arriaga  15 , E Rowlinson  15 , A O Carter  16 , L E Yerkes  16 , W Li  17 , J R Reuer  17 , L J Stockman  18 , T Tang  19 , J T Brooks  1 , E H Teshale  20 , H I Hall  1
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HIV and viral hepatitis coinfection analysis using surveillance data from 15 US states and two cities

K A Bosh et al. Epidemiol Infect. 2018 May.

Abstract

Coinfection with human immunodeficiency virus (HIV) and viral hepatitis is associated with high morbidity and mortality in the absence of clinical management, making identification of these cases crucial. We examined characteristics of HIV and viral hepatitis coinfections by using surveillance data from 15 US states and two cities. Each jurisdiction used an automated deterministic matching method to link surveillance data for persons with reported acute and chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections, to persons reported with HIV infection. Of the 504 398 persons living with diagnosed HIV infection at the end of 2014, 2.0% were coinfected with HBV and 6.7% were coinfected with HCV. Of the 269 884 persons ever reported with HBV, 5.2% were reported with HIV. Of the 1 093 050 persons ever reported with HCV, 4.3% were reported with HIV. A greater proportion of persons coinfected with HIV and HBV were males and blacks/African Americans, compared with those with HIV monoinfection. Persons who inject drugs represented a greater proportion of those coinfected with HIV and HCV, compared with those with HIV monoinfection. Matching HIV and viral hepatitis surveillance data highlights epidemiological characteristics of persons coinfected and can be used to routinely monitor health status and guide state and national public health interventions.

Keywords: Coinfection; HIV/AIDS; Hepatitis B; Hepatitis C; Public Health Surveillance.

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Conflict of interest statement

All health departments receive funding from CDC to support public health surveillance. However, the funding was not specific to this analysis. C.F. reported receiving payment for lectures at John Hopkins University outside of the submitted work and reported his institution received funding through other grants from CDC and the Health Resources and Services Administration. L.H.A. reported receiving payment for writing and reviewing the manuscript as part of job responsibilities as an employee of the Texas Department of State Health Services. L.H.A. serves as a board member for Neuropathy Alliance of Texas. L.H.A. reported her institution received funding from CDC and that Neuropathy Alliance of Texas receives funding from various sources, including St. David's Foundation and Athena Health. B.J. reported her institution received funding for surveillance activities not directly related to activities of this project. S.K. reported her institution received funding to support travel to meetings for other purposes. No other reported conflicts are relevant to the content of the manuscript.

References

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