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Review
. 1987 Oct;42(10):767-86.

Teicoplanin: chemical, physico-chemical and biological aspects

Affiliations
  • PMID: 2963756
Review

Teicoplanin: chemical, physico-chemical and biological aspects

C Coronelli et al. Farmaco Sci. 1987 Oct.

Abstract

The structure determination and the physico-chemical properties of teicoplanin, a new glycopeptide antibiotic of the vancomycin-ristocetin family are presented. Some biological studies and the mechanism of action at the molecular level are discussed. Analytical test methods, such as HPLC assay, bioassay and enzymatic assay are described. The antimicrobial activity of teicoplanin and of some relevant acid and basic hydrolysis products are also discussed.

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