Perioperative concerns and management of pressurised intraperitoneal aerosolised chemotherapy: Report of two cases
- PMID: 29643558
- PMCID: PMC5881326
- DOI: 10.4103/ija.IJA_623_17
Perioperative concerns and management of pressurised intraperitoneal aerosolised chemotherapy: Report of two cases
Abstract
Pressurised intraperitoneal aerosolised chemotherapy (PIPAC) is a new, mostly supportive approach to help patients with advanced peritoneal metastasis to increase the lifespan. It carries occupational hazards to health-care workers and especially anaesthesiologist during the procedure. The aerosolised chemotherapy can also cause chemical peritonitis and organ dysfunction in the perioperative period. In this case report, we present the report of two cases and discuss the perioperative concerns and management related to PIPAC.
Keywords: Aerosols; chemotherapy; occupational; palliative.
Conflict of interest statement
There are no conflicts of interest.
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References
-
- Ceelen WP, Flessner MF. Intraperitoneal therapy for peritoneal tumors: Biophysics and clinical evidence. Nat Rev Clin Oncol. 2010;7:108–15. - PubMed
-
- Matharu G, Tucker O, Alderson D. Systematic review of intraperitoneal chemotherapy for gastric cancer. Br J Surg. 2011;98:1225–35. - PubMed
-
- Gill RS, Al-Adra DP, Nagendran J, Campbell S, Shi X, Haase E, et al. Treatment of gastric cancer with peritoneal carcinomatosis by cytoreductive surgery and HIPEC: A systematic review of survival, mortality, and morbidity. J Surg Oncol. 2011;104:692–8. - PubMed
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