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Case Reports
. 2018 Apr-Jun;33(2):145-147.
doi: 10.4103/ijnm.IJNM_144_17.

Metabolic Bone Superscan in Carcinoma Breast with Occult Graves' Disease: Looking Beyond Skeletal Metastases

Ashwin Singh Parihar  1 , Ashwani Sood  1 , Tinu Thadiyananickal Lukose  1 , Rajeev Kumar Seam  2 , Bhagwant Rai Mittal  1
Affiliations
Case Reports

Metabolic Bone Superscan in Carcinoma Breast with Occult Graves' Disease: Looking Beyond Skeletal Metastases

Ashwin Singh Parihar et al. Indian J Nucl Med. 2018 Apr-Jun.

Abstract

Extrathyroidal manifestations of autoimmune thyroid disorders include thyroid-associated ophthalmopathy, thyroid dermopathy, and thyroid acropachy. Thyroid acropachy is an extreme manifestation of autoimmune thyroid disorder characterized by clubbing and swelling of fingers and toes, with or without periosteal reaction of the distal bones. We present a 50-year-old woman, posttreatment for carcinoma breast (6 years back) and referred for bone scan for generalized body ache. Bone scan findings resulting in detailed clinical evaluation prompted toward the suspicion of a thyroidal disease with ultimate diagnosis of Graves' disease.

Keywords: Metabolic bone disease; metabolic superscan; thyrotoxicosis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
99mTc-MDP whole-body bone scan in anterior and posterior projections, showing increased tracer uptake in the axial and appendicular skeleton, suggestive of metabolic superscan pattern
Figure 2
Figure 2
99mTc-pertechnetate thyroid scan showing increased tracer uptake in both lobes of the enlarged thyroid gland with suppressed salivary gland tracer uptake, suggestive of diffuse toxic goiter
See this image and copyright information in PMC

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