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. 2018 Jun:105:52-62.
doi: 10.1016/j.brat.2018.03.005. Epub 2018 Mar 17.

Interactions between risk factors in the prediction of onset of eating disorders: Exploratory hypothesis generating analyses

Eric Stice  1 , Christopher D Desjardins  2
Affiliations

Interactions between risk factors in the prediction of onset of eating disorders: Exploratory hypothesis generating analyses

Eric Stice et al. Behav Res Ther. 2018 Jun.

Abstract

Objective: Because no study has tested for interactions between risk factors in the prediction of future onset of each eating disorder, this exploratory study addressed this lacuna to generate hypotheses to be tested in future confirmatory studies.

Method: Data from three prevention trials that targeted young women at high risk for eating disorders due to body dissatisfaction (N = 1271; M age 18.5, SD 4.2) and collected diagnostic interview data over 3-year follow-up were combined to permit sufficient power to predict onset of anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD) using classification tree analyses, an analytic technique uniquely suited to detecting interactions.

Results: Low BMI was the most potent predictor of AN onset, and body dissatisfaction amplified this relation. Overeating was the most potent predictor of BN onset, and positive expectancies for thinness and body dissatisfaction amplified this relation. Body dissatisfaction was the most potent predictor of BED onset, and overeating, low dieting, and thin-ideal internalization amplified this relation. Dieting was the most potent predictor of PD onset, and negative affect and positive expectancies for thinness amplified this relation.

Conclusions: Results provided evidence of amplifying interactions between risk factors suggestive of cumulative risk processes that were distinct for each disorder; future confirmatory studies should test the interactive hypotheses generated by these analyses. If hypotheses are confirmed, results may allow interventionists to target ultra high-risk subpopulations with more intensive prevention programs that are uniquely tailored for each eating disorder, potentially improving the yield of prevention efforts.

Keywords: Anorexia nervosa; Binge eating disorder; Bulimia nervosa; Interactions; Prospective; Purging disorder; Risk factors.

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Figures

Figure 1
Figure 1
Classification tree for anorexia nervosa. Note. The gray, rounded nodes are terminal.
Figure 2
Figure 2
Classification tree for bulimia nervosa. Note. The gray, rounded nodes are terminal.
Figure 3
Figure 3
Classification tree for binge eating disorder. Note. The gray, rounded nodes are terminal.
Figure 4
Figure 4
Classification tree for purging disorder. Note. The gray, rounded nodes are terminal.
See this image and copyright information in PMC

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