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. 1988 Feb;23(1-2):69-73.
doi: 10.1007/BF01967192.

Flare up of joint inflammations induced by cloned helper T cells. Retention of the helper T cells

I S Klasen  1 , R M Ladestein, W B van den Berg, R Benner
Affiliations

Flare up of joint inflammations induced by cloned helper T cells. Retention of the helper T cells

I S Klasen et al. Agents Actions. 1988 Feb.

Abstract

Joint inflammations were induced in mice by intra articular (ia) injection of cloned helper T cells specific for methylated bovine serum albumin (mBSA) together with mBSA. Local injection of mBSA several weeks after waning of a joint inflammation induced by cloned helper T cells caused a flare up reaction. This indicates that the helper T cells persisted in the joint after the primary inflammation. In the present paper we show that the helper T cells can also persist for some time in a knee joint in the absence of the specific antigen and/or an inflammatory reaction.

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References

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