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. 2018 Aug 1;175(8):741-755.
doi: 10.1176/appi.ajp.2018.17091048. Epub 2018 Apr 16.

Prevalence and Correlates of Prescription Stimulant Use, Misuse, Use Disorders, and Motivations for Misuse Among Adults in the United States

Wilson M Compton  1 , Beth Han  1 , Carlos Blanco  1 , Kimberly Johnson  1 , Christopher M Jones  1
Affiliations

Prevalence and Correlates of Prescription Stimulant Use, Misuse, Use Disorders, and Motivations for Misuse Among Adults in the United States

Wilson M Compton et al. Am J Psychiatry. .

Abstract

Objective: The authors sought to simultaneously examine the prevalence and correlates of prescription stimulant use, misuse, use disorders, and motivations for misuse in the U.S. adult population.

Method: This was a nationally representative household population study of adults age 18 or older from the 2015 and 2016 National Surveys on Drug Use and Health (N=102,000). Measurements included prescription stimulant use, use without misuse, misuse without use disorders, and misuse with use disorders, as well as sociodemographic characteristics, health conditions, and mental health factors.

Results: Among U.S. adults, 6.6% (annual average) used prescription stimulants overall; 4.5% used without misuse, 1.9% misused without use disorders, and 0.2% had use disorders. Adults with past-year prescription stimulant use disorders did not differ from those with misuse without use disorders in any of the examined sociodemographic characteristics and in many of the examined substance use problems. The most commonly reported motivations for misuse were to help be alert or concentrate (56.3%). The most likely source of misused prescription stimulants was by obtaining them free from friends or relatives (56.9%). More frequent prescription stimulant misuse and use disorder were associated with an increased likelihood of obtaining medications from physicians or from drug dealers or strangers and less likelihood of obtaining them from friends or relatives.

Conclusions: Approximately 16.0 million U.S. adults used prescription stimulants in the preceding year (annual average), 5.0 million misused prescription stimulants, and 0.4 million had use disorders. Cognitive enhancement was the most commonly reported reason for misusing prescription stimulants. Patients who are using their medication for cognitive enhancement or diverting their medication to others present a high risk.

Keywords: CNS Stimulants; Epidemiology; Psychoactive Substance Use Disorder.

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Conflict of interest statement

Conflict of Interest Disclosures

Unrelated to the submitted work, Compton reports ownership of stock in General Electric Co., 3M Co., and Pfizer Inc., and Blanco reports ownership of stock in General Electric, Sanofi, and Eli Lilly, Inc. Han, Johnson, and Jones have no conflicts to disclose.

Comment in

References

    1. Hughes A, Williams MR, Lipari RN, et al. Prescription drug use and misuse in the United States: Results from the 2015 National Survey on Drug Use and Health. NSDUH Data Review. 2016 Sep; http://www.samhsa.gov/data/sites/default/files/NSDUH-FFR2-2015/NSDUH-FFR.... Accessed April 10, 2017.
    1. National Institute on Drug Abuse. How do stimulants affect the brain and body? https://www.drugabuse.gov/publications/research-reports/prescription-dru.... Accessed April 10, 2017.
    1. Martins S, Fenton M, Keyes K, et al. Mood and anxiety disorders and their association with non-medical prescription opioid use and prescription opioid-use disorder: longitudinal evidence from the National Epidemiologic Study on Alcohol and Related Conditions. Psychological Medicine. 2012;42:1261–1272. - PMC - PubMed
    1. Wang Y, Cottler LB, Striley CW. Differentiating patterns of prescription stimulant medical and nonmedical use among youth 10-18 years of age. Drug Alcohol Depend. 2015;157:83–9. - PubMed
    1. Zullig KJ, Divin AL, Weiler RM, et al. Adolescent nonmedical use of prescription pain relievers, stimulants, and depressants, and suicide risk. Subst Use Misuse. 2015;50(13):1678–89. - PubMed

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