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Comment
. 2018 Jun;8(6):666-667.
doi: 10.1158/2159-8290.CD-NB2018-047. Epub 2018 Apr 15.

Adjuvant Therapy for Melanoma Prolongs RFS

No authors listed
Comment

Adjuvant Therapy for Melanoma Prolongs RFS

No authors listed. Cancer Discov. 2018 Jun.

Abstract

The PD-1 inhibitor pembrolizumab may be an effective adjuvant therapy for patients with stage III melanoma. In a clinical trial, patients who received the drug had a 12-month recurrence-free survival rate of 75.4%, compared with 61% for patients who received a placebo.

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  • Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma.
    Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson V, Dalle S, Haydon A, Lichinitser M, Khattak A, Carlino MS, Sandhu S, Larkin J, Puig S, Ascierto PA, Rutkowski P, Schadendorf D, Koornstra R, Hernandez-Aya L, Maio M, van den Eertwegh AJM, Grob JJ, Gutzmer R, Jamal R, Lorigan P, Ibrahim N, Marreaud S, van Akkooi ACJ, Suciu S, Robert C. Eggermont AMM, et al. N Engl J Med. 2018 May 10;378(19):1789-1801. doi: 10.1056/NEJMoa1802357. Epub 2018 Apr 15. N Engl J Med. 2018. PMID: 29658430 Clinical Trial.

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