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. 1988 May;62(5):1814-8.
doi: 10.1128/JVI.62.5.1814-1818.1988.

Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins

J Figge  1 , T Webster, T F Smith, E Paucha
Affiliations

Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins

J Figge et al. J Virol. 1988 May.

Abstract

Regions containing similar elements of primary and predicted secondary structure were identified in simian virus 40 large T, adenovirus E1A, c-myc and v-myc proteins by a computer program with a set of highly specific, complex pattern descriptors. In all cases these regions were localized in domains of the respective proteins known to be required for transforming activity. We suggest that these apparently structurally similar regions may mediate a common biological function.

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