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Case Reports
. 2018 Apr;52(2):154-158.
doi: 10.1007/s13139-017-0488-3. Epub 2017 Jul 25.

Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT

N T K Thanseer  1 , Sanjay Kumar Bhadada  2 , Ashwani Sood  1 , Ashwin Singh Parihar  1 , Divya Dahiya  3 , Priyanka Singh  2 , Rajender Kumar Basher  1 , Ashim Das  4 , Bhagwant R Mittal  1
Affiliations
Case Reports

Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT

N T K Thanseer et al. Nucl Med Mol Imaging. 2018 Apr.

Erratum in

Abstract

18F-Fluorocholine (FCH) PET/CT is evolving as a functional imaging modality for the preoperative imaging of abnormal parathyroid tissue(s) helping to localize eutopic and ectopic parathyroid tissue and limit the extent of surgery. FCH PET/CT may show incidental uptake in various thyroid lesions necessitating further evaluation, whereas the role of 18F-fluorodeoxyglucose (FDG) PET/CT in the detection of incidental thyroid nodules is well documented. The case of a middle-aged woman with dual pathology of parathyroid adenoma and papillary thyroid cancer detected on FCH and FDG PET/CT is presented.

Keywords: 18F-Fluorocholine; 18F-Fluorodeoxyglucose; PET/CT; Papillary thyroid carcinoma; Parathyroid adenoma.

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Conflict of interest statement

Compliance with Ethical StandardsNone.All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.The institutional review board of our institution approved this retrospective study, and the requirement to obtain informed consent was waived.

Figures

Fig. 1
Fig. 1
a, b 99mTc-Sestamibi dual-phase planar images show a focal tracer-avid lesion (arrows) below the left thyroid lobe on both the early (a) and delayed (b) images. c, d SPECT/CT images of the neck and mediastinum: transaxial CT (c) and fused (d) images show a small soft-tissue lesion with tracer avidity inferior to the left thyroid lobe
Fig. 2
Fig. 2
a The 18F-FCH PET/CT MIP image shows an intense tracer-avid focus (thick arrow) in the left lower neck and a faint tracer-avid focus (thin arrow) in the right upper neck. c, d, f, g The transaxial CT and fused images show a right thyroid lobe hypodense lesion with faint tracer uptake and a soft-tissue lesion inferior to the left thyroid lobe with intense tracer uptake. b 18F-FDG PET/CT MIP image shows a tracer-avid focus (thin arrow) in the right upper neck. c, e, f, h Transaxial CT and fused images show a right thyroid lobe hypodense lesion with intense tracer uptake and a small soft-tissue lesion with no tracer uptake inferior to the left thyroid lobe
Fig. 3
Fig. 3
Histopathological examination of the surgical specimens. a, b Photomicrographs of H&E-stained sections show (a) the papillary configuration of the papillary thyroid carcinoma (×40) and (b) the nuclear features of the papillary thyroid carcinoma in the form of optical clearing, overcrowding and grooving (×400). c, d Photomicrographs of H&E-stained sections show (c) normal parathyroid gland (×100), and (d) normal parathyroid at the periphery of the adenoma (×40) and inset the adenoma
See this image and copyright information in PMC

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