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Case Reports
. 2018 May;24(5):933-935.
doi: 10.3201/eid2405.171479.

Spontaneous Abortion Associated with Zika Virus Infection and Persistent Viremia

Case Reports

Spontaneous Abortion Associated with Zika Virus Infection and Persistent Viremia

Anna Goncé et al. Emerg Infect Dis. 2018 May.

Abstract

We report a case of spontaneous abortion associated with Zika virus infection in a pregnant woman who traveled from Spain to the Dominican Republic and developed a rash. Maternal Zika viremia persisted at least 31 days after onset of symptoms and 21 days after uterine evacuation.

Keywords: Dominican Republic; Spain; Zika virus; pregnancy; spontaneous abortion; viremia; viruses.

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Figures

Figure
Figure
Clinical timeline for a 22-year-old pregnant woman who had suspected Zika virus infection. The woman was in the seventh week of gestation when she traveled from Spain to the Dominican Republic. CRL, crown–rump length; DENV, dengue virus; Ig, immunoglobulin; IHC, immunohistochemistry; ZIKV, Zika virus; RT-PCR, reverse transcription PCR; +, positive; –, negative.

References

    1. van der Eijk AA, van Genderen PJ, Verdijk RM, Reusken CB, Mögling R, van Kampen JJ, et al. Miscarriage associated with Zika virus infection. N Engl J Med. 2016;375:1002–4. 10.1056/NEJMc1605898 - DOI - PubMed
    1. Martines RB, Bhatnagar J, de Oliveira Ramos AM, Davi HP, Iglezias SD, Kanamura CT, et al. Pathology of congenital Zika syndrome in Brazil: a case series. Lancet. 2016;388:898–904. 10.1016/S0140-6736(16)30883-2 - DOI - PubMed
    1. Schaub B, Monthieux A, Najihoullah F, Harte C, Césaire R, Jolivet E, et al. Late miscarriage: another Zika concern? Eur J Obstet Gynecol Reprod Biol. 2016;207:240–1. 10.1016/j.ejogrb.2016.10.041 - DOI - PubMed
    1. Bhatnagar J, Rabeneck DB, Martines RB, Reagan-Steiner S, Ermias Y, Estetter LB, et al. Zika virus RNA replication and persistence in brain and placental tissue. Emerg Infect Dis. 2017;23:405–14. 10.3201/eid2303.161499 - DOI - PMC - PubMed
    1. Driggers RW, Ho CY, Korhonen EM, Kuivanen S, Jääskeläinen AJ, Smura T, et al. Zika virus infection with prolonged maternal viremia and fetal brain abnormalities. N Engl J Med. 2016;374:2142–51. 10.1056/NEJMoa1601824 - DOI - PubMed