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. 2018 May;24(5):924-925.
doi: 10.3201/eid2405.152033.

Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease

Masashi Yanagihara, Hidehiro Tsuneoka, Ayano Tanimoto, Ken-Ichiro Otsuyama, Jun Nishikawa, Tomohiro Matsui, Junzo Nojima, Kiyoshi Ichihara

Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease

Masashi Yanagihara et al. Emerg Infect Dis. 2018 May.

Abstract

We used real-time PCR to detect Bartonella henselae DNA in 7.9% (5/63) of blood specimens from seronegative patients in Japan suspected of having cat-scratch disease. The combined use of serologic tests and real-time PCR to analyze blood specimens is recommended for the prompt, noninvasive laboratory diagnosis of cat-scratch disease.

Keywords: Bartonella henselae; Cat-scratch disease; Japan; bacteria; indirect fluorescence antibody assay; peripheral blood; real-time PCR; zoonoses.

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