Inhibiting EBV: The Key to Carefree Smooching
- PMID: 29669245
- DOI: 10.1016/j.immuni.2018.03.036
Inhibiting EBV: The Key to Carefree Smooching
Abstract
There are no vaccines or therapies to treat Epstein-Barr virus (EBV). Snijder et al. (2018) isolated a potent human antibody against EBV that blocks infection of both B cells and epithelial cells. Structural analysis of the antibody complexed with a viral surface protein complex identified a site that may be useful in vaccine development.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.Immunity. 2018 Apr 17;48(4):799-811.e9. doi: 10.1016/j.immuni.2018.03.026. Immunity. 2018. PMID: 29669253 Free PMC article.
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