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. 2018 Apr 5:12:651-656.
doi: 10.2147/OPTH.S158785. eCollection 2018.

Retinal detachment in albinism

Ahmad M Mansour  1   2 , Jay Chhablani  3 , J Fernando Arevalo  4   5 , Lihteh Wu  6 , Ravi Sharma  3 , Suthasinee Sinawat  7 , Tharikarn Sujirakul  8 , Alexandre Assi  9 , Wandsy M Vélez-Vázquez  10 , Mohamad A Mansour  1 , Ozcan Kayikcioglu  11 , Cem Kucukerdonmez  12 , Ali Kal  13
Affiliations

Retinal detachment in albinism

Ahmad M Mansour et al. Clin Ophthalmol. .

Abstract

Purpose: To report the visual and anatomic outcomes of albino retinal detachment (ARD) repair.

Methods: Collaborative retrospective analysis of ARD. Outcome measures were number of surgical interventions, final retinal reattachment, and best corrected visual acuity (BCVA) at last follow-up.

Results: Seventeen eyes of 16 patients (12 males; mean age =37.8 years) had the following complications at presentation: macula off (14), total (7) or inferior detachment (5), proliferative vitreoretinopathy (5), detectable break (16), lattice (5), horseshoe tears (9), and giant tear or dialysis (4). Mean number of interventions was 1.8 (range =1-5) and included cryopexy (15) with scleral buckle (11), and/or vitrectomy (8). Mean initial BCVA was counting finger (CF) 1 m and at last follow-up (mean 77 months) CF4m with mean improvement of 4.5 lines (early treatment diabetic retinopathy study) (P=0.05). Intraoperative choroidal hemorrhage occurred in three eyes. The retina was finally attached in 14 eyes, with residual inferior detachment in three eyes with silicone oil in situ. Silicone oil was kept in six of seven eyes because of residual inferior detachment (3) and removal of silicone oil, which led to redetachment (1) or fear of redetachment (2).

Conclusion: Repair of ARD may require several interventions, with the need to keep silicone oil in several cases due to nystagmus and reduced melanin pigment.

Keywords: cryopexy; foveal hypoplasia; nystagmus; retinal detachment; scleral buckle; silicone oil; vitrectomy.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flow chart of the pathophysiology of retinal detachment in albinos. Abbreviation: RPE, retinal pigment epithelium.
See this image and copyright information in PMC

References

    1. Sinha MK, Chhablani J, Shah BS, Narayanan R, Jalali S. Surgical challenges and outcomes of rhegmatogenous retinal detachment in albinism. Eye. 2016;30:422–425. - PMC - PubMed
    1. Yang JW, Lee SJ, Kang SB, Park YH. A case of retinal detachment surgery in albinism patient. J Korean Ophthalmol Soc. 2008;49:840–844.
    1. Hiroshi M, Hiroyuki M. A case of ocular albinism with rhegmatogenous retinal detachment. Jap Rev Clin Ophthalmol. 1999;93:861–864.
    1. Mal W, Zafar S, Siddiqi S, Rizvi SF. Retinal detachment surgery in oculocutaneous albino patient. Pak J Ophthalmol. 2013;29:235–237.
    1. Machemer R, Aaberg TM, Freeman HM, Irvine AR, Lean JS, Michels RM. An updated classification of retinal detachment with proliferative vitreoretinopathy. Am J Ophthalmol. 1991;112:159–165. - PubMed

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