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Case Reports
. 2018 Feb 19:2018:7419823.
doi: 10.1155/2018/7419823. eCollection 2018.

Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis

Cassandra C Lautredou  1 , Joshua S Hardin  2 , John R Chancellor  2 , Sami H Uwaydat  2 , Abdallah A Ellabban  3 , Ahmed B Sallam  2
Affiliations
Case Reports

Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis

Cassandra C Lautredou et al. Case Rep Ophthalmol Med. .

Abstract

Purpose: To report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis.

Methods/patients: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants.

Results: Treatment led to the resolution of CME and improvement in visual acuity.

Conclusions: Intravitreal corticosteroid therapy may be a viable adjunctive treatment for refractory CME in patients with treated syphilitic uveitis. Corticosteroid-induced exacerbation of infection is unlikely in patients with an adequate serologic treatment response.

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Figures

Figure 1
Figure 1
(a) Infrared fundus photo of the macula showing cystoid macular edema (CME); (b) optical coherence tomography (OCT) of the macula showing CME prior to treatment; (c) macular OCT showing resolution of CME with small amount of subretinal fluid; (d) color fundus photo after resolution of retinitis with white arrow pointing to the dexamethasone intravitreal implant; (e) autofluorescence fundus photo demonstrating temporal hypofluorescent changes that represent scarring following syphilitic retinitis.
See this image and copyright information in PMC

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