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. 2018 Jun;33(7):463-467.
doi: 10.1177/0883073818767039. Epub 2018 Apr 19.

Pediatric Stroke Rates Over 17 Years: Report From a Population-Based Study

Laura L Lehman  1 , Jane C Khoury  2 , J Michael Taylor  3 , Samrat Yeramaneni  2   4 , Heidi Sucharew  2 , Kathleen Alwell  5 , Charles J Moomaw  5 , Katrina Peariso  3 , Matthew Flaherty  5 , Pooja Khatri  5 , Joseph P Broderick  5 , Brett M Kissela  5 , Dawn O Kleindorfer  5
Affiliations

Pediatric Stroke Rates Over 17 Years: Report From a Population-Based Study

Laura L Lehman et al. J Child Neurol. 2018 Jun.

Abstract

We previously published rates of pediatric stroke using our population-based Greater Cincinnati Northern Kentucky Stroke Study (GCNK) for periods July 1993-June 1994 and 1999. We report population-based rates from 2 additional study periods: 2005 and 2010. We identified all pediatric strokes for residents of the GCNK region that occurred in July 1, 1993-June 30, 1994, and calendar years 1999, 2005, and 2010. Stroke cases were ascertained by screening discharge ICD-9 codes, and verified by a physician. Pediatric stroke was defined as stroke in those <20 years of age. Stroke rates by study period, overall, by age and by race, were calculated. Eleven children died within 30 days, yielding an all-cause case fatality rate of 15.7% (95% confidence interval 1.1%, 26.4%) with 3 (27.3%) ischemic, 6 (54.5%) hemorrhagic, and 2 (18.2%) unknown stroke type. The pediatric stroke rate of 4.4 per 100 000 in the GCNK study region has not changed over 17 years.

Keywords: children; epidemiology; outcome; pediatric; stroke.

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Conflict of interest statement

Conflicts of interest: No conflicts of interest for L.L.L., J.C.K, J.M.T, S.Y., H.S., K.A., C.J.M., K.P., M.F., J.P.B., B.M.K., D.O.K. P.K. discloses that University of Cincinnati Department of Neurology is paid by Genentech for her research effort as PRISMS PI

Figures

Figure 1
Figure 1
Incidence/100,000, with the 95% confidence interval, of childhood stroke stratified by age group
See this image and copyright information in PMC

References

    1. Kochanek KDXJ, Murphy SL, Minino AM, Kung H. Deaths: Final Data for 2009. Natl Vital Stat Rep. 2011;60(3):1–167. - PubMed
    1. Lehman LL, Fullerton HJ. Changing Ethnic Disparity in Ischemic Stroke Mortality in US Children After the STOP Trial. JAMA Pediatr. 2013:1–5. - PubMed
    1. Fullerton HJ, Wu YW, Zhao S, Johnston SC. Risk of stroke in children: ethnic and gender disparities. Neurology. 2003;61:189–94. - PubMed
    1. Golomb MR, Fullerton HJ, Nowak-Gottl U, Deveber G. Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study. Stroke. 2009;40:52–7. - PubMed
    1. Lo W, Stephens J, Fernandez S. Pediatric stroke in the United States and the impact of risk factors. J Child Neurol. 2009;24:194–203. - PMC - PubMed

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