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Case Reports
. 2018 May;66(5):699-701.
doi: 10.4103/ijo.IJO_936_17.

Corneal fibroma: An uncommon stromal tumor

Affiliations
Case Reports

Corneal fibroma: An uncommon stromal tumor

Akshay Gopinathan Nair et al. Indian J Ophthalmol. 2018 May.

Abstract

A 56-year-old male patient presented with a slow-growing, elevated, smooth, white corneal mass. The mass was excised by performing an alcohol-assisted keratoepitheliectomy and sent for histopathological examination. Subepithelially, closely packed spindle cells in "feather-stitched" or storiform pattern were seen. Immunohistochemically, the cells stained negatively for CD-34 and S-100 and focal positivity was seen for vimentin. Based on the morphology and immunochemical staining, a diagnosis of corneal fibroma was made. No recurrence was seen. Corneal fibroma is an exceedingly rare, benign tumor and possibly lies on the same spectrum as corneal keloid and hypertrophic cicatrix. Surgical resection is usually curative.

Keywords: Cicatrix; corneal keloid; dermoid; limbus; neoplasm; ocular surface squamous neoplasm.

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Conflict of interest statement

There are no conflicts of interest

Figures

Figure 1
Figure 1
A clinical picture of the corneal mass. Note the few intralesional blood vessels and the feeder vessel inferiorly
Figure 2
Figure 2
A photomicrograph of the excised mass. The epithelium above is intact and subepithelially, closely packed spindle cells in a “feather-stitched” or storiform pattern can be seen (H and E, ×40)

References

    1. Charles NC, Ostriker GE. Epibulbar conjunctival fibroma. Ophthal Plast Reconstr Surg. 2007;23:249–50. - PubMed
    1. Herschorn BJ, Jakobiec FA, Hornblass A, Iwamoto T, Harrison WG. Epibulbar subconjunctival fibroma. A tumor possibly arising from tenon's capsule. Ophthalmology. 1983;90:1490–4. - PubMed
    1. Hayat K, Shahzad M, Lin Z, Miao L, Xue S. Surgical therapy of unusual congenital corneal fibroma. J Ayub Med Coll Abbottabad. 2010;22:180–2. - PubMed
    1. Al-Katan HM, Al-Arfaj KM. Corneal keloid: Case report and literature review. Saudi J Ophthalmol. 2007;21:130–4.
    1. Alkatan HM, Al-Arfaj KM, Hantera M, Al-Kharashi S. Healed corneal ulcer with keloid formation. Saudi J Ophthalmol. 2012;26:245–8. - PMC - PubMed

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