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Case Reports
. 2018 May;66(5):717-719.
doi: 10.4103/ijo.IJO_1108_17.

Optic nerve aplasia: A case series

K Samyukta Sadasivan  1 , Neelam Pawar  1 , Meenakshi Ravindran  1 , Ramakrishnan Rengappa  2
Affiliations
Case Reports

Optic nerve aplasia: A case series

K Samyukta Sadasivan et al. Indian J Ophthalmol. 2018 May.

Abstract

Optic nerve aplasia (ONA) is a congenital optic nerve anomaly characterized by the absence of optic nerve head, retinal blood vessels, retinal ganglion cells, and optic nerve fibers in a malformed eye. Clinically, the condition presents with the absence of perception of light, afferent pupillary defect and a fundus appearance of absent optic nerve head, and retinal vessels with associated ocular and nonocular abnormalities. Systemic anomalies have been reported with bilateral ONA, whereas unilateral ONA is seen in otherwise healthy individuals. We report three cases of ONA with varied clinical presentations.

Keywords: Aplasia of optic nerve; central nervous system anomaly; congenital optic nerve anomaly.

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Conflict of interest statement

There are no conflicts of interest

Figures

Figure 1
Figure 1
Fundus appearance of absent optic nerve head and retinal vessels in the right eye, normal fundus of the left eye, and coronal magnetic resonance imaging showing the absence of optic nerve in the expected location in the right eye. Optic nerve is of normal caliber and seen in the intraconal fat in the left eye, marked with arrow (Case no: 1)
Figure 2
Figure 2
Normally appearing fundus in the right eye and absence of optic nerve in the left eye (Case no: 2)
Figure 3
Figure 3
Fundus photograph of the right eye and left eye showing complete absence of the optic nerve head and retinal vessels and coronal magnetic resonance imaging showing bilateral absence of optic nerve (Case no: 3)
See this image and copyright information in PMC

References

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Publication types

Supplementary concepts