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Comment
. 2018 Oct;102(10):1593-1594.
doi: 10.1097/TP.0000000000002238.

Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function

Kannan P Samy  1 , Todd V Brennan  2
Affiliations
Comment

Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function

Kannan P Samy et al. Transplantation. 2018 Oct.
No abstract available

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1. Dendritic cell phenotype governs localization and function
Inflammatory signals in peripheral tissues cause DC activation and maturation into mDCs. Based on the upregulation of specific chemokine receptors and adhesion molecules, mDCs traffic to lymph nodes and promote immune stimulation. Circulating from healthy peripheral tissues, imDCs can bypass lymph nodes and migrate to the thymus and promote immune tolerance to peripheral antigen. Illustrated by Megan Llewellyn, MSMI; copyright Duke University; with permission under a CC BY-ND 4.0 license
See this image and copyright information in PMC

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References

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