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Comment
. 2018 Apr 19;70(2):193-194.
doi: 10.1016/j.molcel.2018.04.003.

Chilled in Translation: Adapting to Bacterial Climate Change

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Chilled in Translation: Adapting to Bacterial Climate Change

Susan Gottesman. Mol Cell. .
Free article

Abstract

Cold-shocked bacteria transiently shut down protein translation, but the mechanisms whereby they adaptively restore translation were incompletely understood. Zhang et al. (2018) demonstrate a global increase in mRNA structure after cold shock and that, as structured RNA decreases, translation returns, dependent upon ribonuclease RNase R and cold shock protein CspA and its homologs.

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