Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes
- PMID: 29677489
- DOI: 10.1016/j.molcel.2018.04.004
Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes
Abstract
Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition, they show that multiple promoters can access the same enhancer without competition, potentially sharing a pool of factors in a transcriptional "hub."
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Visualization of Transvection in Living Drosophila Embryos.Mol Cell. 2018 Apr 19;70(2):287-296.e6. doi: 10.1016/j.molcel.2018.02.029. Epub 2018 Mar 29. Mol Cell. 2018. PMID: 29606591 Free PMC article.
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