[Nondisjunction of the chromosomes in man. Hypotheses and facts]
- PMID: 2967787
[Nondisjunction of the chromosomes in man. Hypotheses and facts]
Abstract
The data on nondisjunction of chromosomes in man, and particularly on chromosome 21 in Down syndrome, are presented in this review. New experimental data obtained by the differential staining technique are considered. These data enable us to revise a number of hypotheses on the causes and mechanisms of chromosome nondisjunction.