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. 2018 May;28(5):328-330.
doi: 10.1016/j.annepidem.2018.03.001. Epub 2018 Mar 6.

Stage-specific incidence rates and trends of prostate cancer by age, race, and ethnicity, United States, 2004-2014

Jun Li  1 , David A Siegel  2 , Jessica B King  3
Affiliations

Stage-specific incidence rates and trends of prostate cancer by age, race, and ethnicity, United States, 2004-2014

Jun Li et al. Ann Epidemiol. 2018 May.

Abstract

Purpose: Current literature shows different findings on the contemporary trends of distant-stage prostate cancer incidence, in part, due to low study population coverage and wide age groupings. This study aimed to examine the stage-specific incidence rates and trends of prostate cancer by age (5-year grouping), race, and ethnicity using nationwide cancer registry data.

Methods: Data on prostate cancer cases came from the 2004-2014 United States Cancer Statistics data set. We calculated stage-specific incidence and 95% confidence intervals by age (5-year age grouping), race, and ethnicity. To measure the changes in rates over time, we calculated annual percentage change (APC).

Results: We identified 2,137,054 incident prostate cancers diagnosed during 2004-2014, with an age-adjusted incidence rate of 453.8 per 100,000. Distant-stage prostate cancer incidence significantly decreased during 2004-2010 (APC = -1.2) and increased during 2010-2014 (APC = 3.3). Significant increases in distant prostate cancer incidence also occurred in men aged older than or equal to 50 years except men aged 65-74 and older than or equal to 85 years, in men with white race (APC = 3.9), and non-Hispanic ethnicity (APC = 3.5).

Conclusions: Using data representing over 99% of U.S. population, we found that incidence rates of distant-stage prostate cancer significantly increased during 2010-2014 among men in certain ages, in white, and with non-Hispanic ethnicity.

Keywords: Cancer incidence; Cancer stage; Prostate cancer.

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Conflict of interest statement

No financial conflict of interest for all authors and no funding sources claimed.

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