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Review
. 2018 Sep;34(9):1799-1801.
doi: 10.1007/s00381-018-3806-x. Epub 2018 Apr 22.

Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature

Ebru Arhan  1   2 , Ayşe Serdaroğlu  3 , Tuğba Hirfanoğlu  3 , Gökhan Kurt  4
Affiliations
Review

Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature

Ebru Arhan et al. Childs Nerv Syst. 2018 Sep.

Abstract

Background: We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output.

Objective: A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus.

Conclusion: We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.

Keywords: Epilepsy; Seizures; Vagal nerve stimulation.

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