Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018:138:81-93.
doi: 10.1016/bs.irn.2018.01.003. Epub 2018 Feb 28.

Response Expectancy and the Placebo Effect

Affiliations
Review

Response Expectancy and the Placebo Effect

Irving Kirsch. Int Rev Neurobiol. 2018.

Abstract

In this chapter, I review basic tenets of response expectancy theory (Kirsch, 1985), beginning with the important distinction between response expectancies and stimulus expectancies. Although both can affect experience, the effects of response expectancies are stronger and more resistant to extinction than those of stimulus expectancies. Further, response expectancies are especially important to understanding placebo effects. The response expectancy framework is consistent with and has been amplified by the Bayesian model of predictive coding. Clinical implications of these phenomena are exemplified.

Keywords: Automaticity; Placebo effects; Predictive coding; Response expectancy; Stimulus expectancy.

PubMed Disclaimer

MeSH terms

LinkOut - more resources