Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Feb 27:2018:6135080.
doi: 10.1155/2018/6135080. eCollection 2018.

Higher Income and Integration into the Workforce Are the Main Factors Associated with Quality of Life in Acromegalic Patients in Northeastern Brazil

Adriana Maria GuimarãesSá  1 , Pedro Antônio Muniz Ferreira  2 , Marinilde Teles Souza  3 , Gilvan Cortês Nascimento  2 , Sabrina da Silva Pereira Damianse  2 , Viviane Chaves de Carvalho Rocha  2 , Manuel Dos Santos Faria  4 , Adalgisa de Souza Paiva Ferreira  5
Affiliations

Higher Income and Integration into the Workforce Are the Main Factors Associated with Quality of Life in Acromegalic Patients in Northeastern Brazil

Adriana Maria GuimarãesSá et al. Int J Endocrinol. .

Abstract

Objective: To identify the factors associated with quality of life in patients with acromegaly with follow-up at the referral service in neuroendocrinology of the state of Maranhão, northeast Brazil.

Methods: The Acromegaly Quality of Life Questionnaire (Acro-QoL) was used. Factors independently associated with quality of life were identified using multivariate linear regression, with p values < 0.05 considered significant.

Results: The multivariate linear regression analysis indicated a positive association between being integrated into the job market and quality of life scores in the overall domain (β = 0.288, p = 0.003), psychological domain (β = 0.291, p = 0.032), and personal relationship domain (β = 0.314, p = 0.019). We also observed a positive association with income and the quality of life scores in all domains as follows: overall domain (β = 0.037, p = 0.003), physical domain (β = 0.988, p = 0.001), psychological domain (β = 0.342, p = 0.008), physical appearance domain (β = 0.270, p = 0.049), and personal relationship domain (β = 0.315, p = 0.012).

Conclusion: For patients with acromegaly living in one of the least developed regions of Brazil, integration into the job market and a higher income were associated with a better quality of life.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Melmed S. Mechanisms for pituitary tumorigenesis: the plastic pituitary. Journal of Clinical Investigation. 2003;112(11):1603–1618. doi: 10.1172/JCI20401. - DOI - PMC - PubMed
    1. Feenstra J., de Herder W. W., ten Have S. M., et al. Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly. Lancet. 2005;365(9471):1644–1646. doi: 10.1016/S0140-6736(05)63011-5. - DOI - PubMed
    1. Anagnostis P., Efstathiadou Z. A., Charizopoulou M., et al. Psychological profile and quality of life in patients with acromegaly in Greece. Is there any difference with other chronic diseases? Endocrine. 2014;47(2):564–571. doi: 10.1007/s12020-014-0166-5. - DOI - PubMed
    1. Biermasz N. R., van Thiel S. W., Pereira A. M., et al. Decreased quality of life in patients with acromegaly despite long-term cure of growth hormone excess. The Journal of Clinical Endocrinology & Metabolism. 2004;89(11):5369–5376. doi: 10.1210/jc.2004-0669. - DOI - PubMed
    1. Guitelman M., Abreu A., Espinosa-de-los-Monteros A. L., Mercado M. Patient-focussed outcomes in acromegaly. Pituitary. 2014;17(S1):18–23. doi: 10.1007/s11102-013-0519-8. - DOI - PMC - PubMed

LinkOut - more resources