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Case Reports
. 2018 Feb 25:2018:2956387.
doi: 10.1155/2018/2956387. eCollection 2018.

From Postural Orthostatic Tachycardia Syndrome to Radiologically Isolated Syndrome

Richa Tripathi  1 , Evanthia Bernitsas  2
Affiliations
Case Reports

From Postural Orthostatic Tachycardia Syndrome to Radiologically Isolated Syndrome

Richa Tripathi et al. Case Rep Neurol Med. .

Abstract

Background: Autonomic dysfunction is common in Multiple Sclerosis (MS) patients. Most spinal cord lesions entail some degree of autonomic nervous system dysfunction. MS patients may develop autonomic dysfunction later in their disease course.

Methods: We report a patient with no prior history of MS presenting with orthostatic symptoms and diagnosed initially with postural orthostatic tachycardia syndrome (POTS). Four months later, she was diagnosed with radiologically isolated syndrome (RIS). The diagnosis was supported by imaging and CSF analysis.

Conclusion: Our case sheds light on the need to consider autonomic dysfunction as an initial presentation of demyelinating pathology. Larger trials are needed to outline the possible association between POTS and RIS.

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Figures

Figure 1
Figure 1
Sagittal T2-weighted images of the cervical spine showing abnormal signal cord at C2 and C4-5 level (arrows).
Figure 2
Figure 2
FLAIR sagittal images of the brain showing pericallosal hyperintensities. FLAIR: fluid- attenuated inversion recovery (arrows).
See this image and copyright information in PMC

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