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Meta-Analysis
. 2019 Jan;10(1):154-162.
doi: 10.1111/jdi.12854. Epub 2018 May 27.

Prevalence of gestational diabetes mellitus in mainland China: A systematic review and meta-analysis

Chenghan Gao  1 , Xin Sun  2 , Li Lu  2 , Fangwei Liu  2 , Jing Yuan  2
Affiliations
Meta-Analysis

Prevalence of gestational diabetes mellitus in mainland China: A systematic review and meta-analysis

Chenghan Gao et al. J Diabetes Investig. 2019 Jan.

Abstract

Aims/introduction: Pregnant women with gestational diabetes mellitus (GDM) are at a higher risk of adverse pregnancy outcomes. The aim of the present study was to estimate the pooled prevalence of GDM in mainland China according to International Association of Diabetes and Pregnancy Study Groups criteria.

Materials and methods: We carried out a systematic review by searching both English and Chinese literature databases. Random effects models were used to summarize the prevalence of GDM in mainland China. Subgroup and sensitivity analyses were carried out to address heterogeneity. Publication bias was evaluated using Egger's test.

Results: A total of 25 papers were included in the meta-analysis, involving 79,064 Chinese participants. The total incidence of GDM in mainland China was 14.8% (95% confidence interval 12.8-16.7%). Subgroup analysis showed that the age, bodyweight and family history of diabetes mellitus could significantly increase the incidence of GDM.

Conclusions: To the best of our knowledge, this systematic review is the first to estimate the pooled prevalence of GDM among women in mainland China according to International Association of Diabetes and Pregnancy Study Groups criteria. The results of our systematic review suggest a high prevalence of GDM in mainland China, indicating that this country might have the largest number of GDM patients worldwide.

Keywords: China; Gestational diabetes mellitus; Prevalence.

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Figures

Figure 1
Figure 1
Flow chart showing the detailed procedure for the inclusion or exclusion of studies.
Figure 2
Figure 2
Forest plots for total incidence of gestational diabetes mellitus (GDM) in mainland China. The diamond represents the pooled odds ratio and 95% confidence interval.
Figure 3
Figure 3
The results of sensitivity analysis of the meta‐analysis.
See this image and copyright information in PMC

References

    1. American Diabetes Association . Classification and diagnosis of diabetes. Diabetes Care 2016; 39: S13–S22. - PubMed
    1. Petry CJ. Gestational diabetes: risk factors and recent advances in its genetics and treatment. Br J Nutr 2010; 104: 775–787. - PubMed
    1. Metzger BE, Lowe LP, Dyer AR, et al Hyperglycemia and adverse pregnancy outcomes. N Engl J Med 2008; 358: 1991–2002. - PubMed
    1. Metzger BE, Gabbe SG, Persson B, et al International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care 2010; 33: 676–682. - PMC - PubMed
    1. World Health Organization . Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy. Diabetes Res Clin Pract 2013; 103: 341–363. - PubMed