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Review
. 2018 Nov-Dec;29(6):835-848.
doi: 10.1016/j.jana.2018.03.005. Epub 2018 Apr 5.

PrEParing Women to Prevent HIV: An Integrated Theoretical Framework to PrEP Black Women in the United States

Crystal Chapman Lambert, Jeanne Marrazzo, K Rivet Amico, Michael J Mugavero, Latesha Elopre
Review

PrEParing Women to Prevent HIV: An Integrated Theoretical Framework to PrEP Black Women in the United States

Crystal Chapman Lambert et al. J Assoc Nurses AIDS Care. 2018 Nov-Dec.

Abstract

Preexposure prophylaxis (PrEP) with optimal adherence has demonstrated efficacy in reducing HIV incidence in women. Black women are disproportionately burdened by the HIV epidemic, accounting for more than half of all new HIV cases in women, thereby making PrEP an ideal prevention strategy for this group. However, to date, PrEP uptake by women in the United States has been slow. Further domestic research is needed to understand the multilevel factors related to PrEP awareness, uptake, and implementation in Black women. Our purpose was to review the current status of HIV prevention in Black women. We summarize clinical trials germane to federal approval of PrEP; discuss important PrEP studies focused on women, including non-oral options; and review multilevel barriers to PrEP uptake. Lastly, we discuss the use of an integrated theoretical framework to organize multilevel factors related to PrEP uptake by Black women in order to guide intervention development.

Keywords: Anderson's Behavioral Model; Black women; HIV; preexposure prophylaxis (PrEP); situated-Information Motivation Behavioral Model.

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Conflict of interest statement

Disclosures

The authors report no real or perceived vested interests that relate to this article that could be construed as a conflict of interest.

Figures

Figure 1.
Figure 1.
Conceptual Model – Grounded in ABM with sIMB Constructs for Intervention Development. Note. Conceptual model adapted from Andersen Health Care Utilization Model (ABM), incorporating constructs from situated, Information, Motivation, Behavioral Skills model (sIMB). Items in boxes are constructs of ABM and sIMB, with arrows relating their interactions. PrEP = pre-exposure prophylaxis; IMB = information, motivation, and behavioral skills model.
See this image and copyright information in PMC

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