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Comment
. 2018 Jul 1;24(13):2981-2983.
doi: 10.1158/1078-0432.CCR-18-0463. Epub 2018 Apr 23.

Cycling Toward Progress: Ribociclib, a CDK 4/6 Inhibitor for Breast Cancer

Laura Spring  1 , Aditya Bardia  2
Affiliations
Comment

Cycling Toward Progress: Ribociclib, a CDK 4/6 Inhibitor for Breast Cancer

Laura Spring et al. Clin Cancer Res. .

Abstract

Ribociclib is an orally active, highly selective inhibitor of cyclin-dependent kinase (CDK) 4 and 6. It is the second CDK 4/6 inhibitor approved for hormone receptor-positive breast cancer. The addition of ribociclib to an aromatase inhibitor has resulted in marked improvements in progression-free survival for patients with metastatic breast cancer. Clin Cancer Res; 24(13); 2981-3. ©2018 AACRSee related article by Shah et al., p. 2999.

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