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Case Reports
. 2018 Jan 4;31(1):102-104.
doi: 10.1080/08998280.2017.1400296. eCollection 2018 Jan.

Bartonella endocarditis with glomerulonephritis in a patient with complete transposition of the great arteries

Helen Hashemi  1 , Tiana R Endicott-Yazdani  1 , Christopher Oguayo  1 , David M Harmon  2 , Tuan Tran  3 , Ginger Tsai-Nguyen  4 , Raul Benavides  3 , Cedric W Spak  5 , Hoang-Lan Nguyen  6
Affiliations
Case Reports

Bartonella endocarditis with glomerulonephritis in a patient with complete transposition of the great arteries

Helen Hashemi et al. Proc (Bayl Univ Med Cent). .

Abstract

We describe a patient with history of dextro-transposition of the great vessels, ventricular septal defect, and pulmonary valve replacement who presented with fatigue, prolonged fever, and leg edema. He was found to have kidney injury, pancytopenia, and liver congestion. Echocardiogram revealed thickened leaflets with prolapsing vegetation on the pulmonary valve. Given the negative blood cultures, high Bartonella henselae immunogobulin G titer (≥1:1024) and positive immunoglobulin M titer (≥1:20), he was diagnosed with Bartonella endocarditis complicated with glomerulonephritis.

Keywords: Bartonella henselae; culture-negative endocarditis; glomerulonephritis; prosthetic valve.

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Figures

Figure 1.
Figure 1.
Photomicrographs of the patient's kidney biopsy demonstrating focal segmental proliferative glomerulonephritis with incomplete crescent formation. Representative areas showing segmental sclerosis with crescent formation in a glomerulus on (a) hematoxylin and eosin–stained tissue section, (b) periodic acid–Schiff-stained tissue section, and (c) trichrome-stained tissue section (200× magnification). (d) Bright granular immunoglobulin M immunofluorescence positivity in a mesangial pattern.
See this image and copyright information in PMC

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