Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Apr;7(2):130-4.
doi: 10.1007/BF01963065.

Poor efficacy of teicoplanin in treatment of deep-seated staphylococcal infections

N Galanakis  1 , H Giamarellou, N Vlachogiannis, C Dendrinos, G K Daikos
Affiliations

Poor efficacy of teicoplanin in treatment of deep-seated staphylococcal infections

N Galanakis et al. Eur J Clin Microbiol Infect Dis. 1988 Apr.

Abstract

Teicoplanin in a 400 mg intravenous loading dose followed by 200 mg/day intravenously or intramuscularly was given to 19 patients with deep-seated staphylococcal infections. Only eight patients (44.4%) were considered cured, failure mostly being observed in patients with osteomyelitis, endocarditis and bacteremia. Poor tissue kinetics of teicoplanin and the presence of foreign bodies are probable explanations for the reported failures. Future trials using a higher dose of teicoplanin with or without the addition of rifampicin or gentamicin seem to be justified.

PubMed Disclaimer

References

    1. J Antimicrob Chemother. 1983 May;11(5):419-25 - PubMed
    1. Am J Med. 1985 Jun 28;78(6B):116-27 - PubMed
    1. J Antimicrob Chemother. 1984 Nov;14(5):441-5 - PubMed
    1. Am J Clin Pathol. 1966 Apr;45(4):493-6 - PubMed
    1. J Infect Dis. 1987 Feb;155(2):187-91 - PubMed

Publication types

MeSH terms

LinkOut - more resources