Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Aug;46(8):3262-3267.
doi: 10.1177/0300060518770958. Epub 2018 Apr 24.

Analysis of orthopedic surgery of patients with metastatic bone tumors and pathological fractures

Resit Sevimli  1 , Mehmet Fatih Korkmaz  1
Affiliations

Analysis of orthopedic surgery of patients with metastatic bone tumors and pathological fractures

Resit Sevimli et al. J Int Med Res. 2018 Aug.

Abstract

Objective This study was performed to determine the most common causes, locations, and treatments of metastasizing primary tumors through evaluation of patients with metastatic bone tumors who were admitted to our clinic. Methods In total, 96 patients with metastatic bone tumors who were admitted to our clinic from 2000 to 2016 were included in the study. Results The breast (30 patients, 31.3%) and lung (18 patients, 18.8%) were the most commonly metastasized primary organs. The femur was the most commonly metastasized bone. Conclusions Bone tumors in patients of advanced age are, unless otherwise proven, considered to be metastatic, and the development of specific diagnostic and treatment algorithms is needed. Clinicians should attempt to improve the general condition of patients with tumors exhibiting bone metastasis to increase the patients' quality of life by providing early mobilization. Thus, appropriate patient selection and proper internal fixation are essential.

Keywords: Bone tumor; bone localization; femur; metastasis; pathological fracture; primary organs.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Localization of metastasizing primary tumors.
Figure 2.
Figure 2.
Symptoms on admission.
Figure 3.
Figure 3.
Treatments administered.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Azad GK, Taylor B, Rubello D, et al. Molecular and functional imaging of bone metastases in breast and prostate cancers: an overview. Clin Nucl Med 2016; 41: 44–50. - PubMed
    1. Lan LS, Ping YJ, Na WL, et al. Down-regulation of toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model. Mol Pain 2010; 6: 2. - PMC - PubMed
    1. Bellido T, Plotkin LI. Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability. Bone 2011; 49: 50–55. - PMC - PubMed
    1. Body JJ. Bisphosphonates for malignancy-related bone disease: current status, future developments. Support Care Cancer 2006; 14: 408–418. - PubMed
    1. Zhu YF, Ungart R, Seidtlitz E, et al. Differences in electrophysiological properties of functionally identified nociceptive sensory neurons in an animal model of cancer-induced bone pain. Mol Pain 2016; 1: 3. - PMC - PubMed

LinkOut - more resources