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Comment
. 2018 Sep 1;24(17):4059-4061.
doi: 10.1158/1078-0432.CCR-18-0491. Epub 2018 Apr 24.

Immunotherapy for Glioblastoma: Playing Chess, Not Checkers

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Immunotherapy for Glioblastoma: Playing Chess, Not Checkers

Christopher M Jackson et al. Clin Cancer Res. .

Abstract

Patients with glioblastoma (GBM) exhibit a complex state of immune dysfunction involving multiple mechanisms of local, regional, and systemic immunosuppression and tolerance. These pathways are now being identified and their relative contributions explored. Delineating how these pathways are interrelated is paramount to effectively implementing immunotherapy for GBM. Clin Cancer Res; 24(17); 4059-61. ©2018 AACRSee related articles by Woroniecka et al., p. 4175 and Mohme et al., p. 4187.

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